逐句驗證分析

「We envision that it would be an ideal alternative for patients who pursue esthetic orthodontic treatment but were not likely to take lingual appliances or clear aligners.」

「Proper selection of cases and reasonable design in clear aligner treatment are expected to obtain tooth alignment, good intercuspation, normal overbite and overjet, periodontal health, parallel roots, and to achieve the goal of aesthetic, functional, stable, and healthy orthodontic treatment. 术者诊断设计不当、矫治技术应用失误、正畸治疗后的复发以及患者依从性较差无法配合矫治等原因可导致患者对矫治结果不满意，寻求二次矫治。此类患者通常已减数，或伴牙周、关节、牙体或缺牙等问题，常需多学科联合治疗，二次矫治难度较大，可选方案受限。无托槽隐形矫治舒适美观，具备数字化精准化程度高、可个性化排牙模拟矫治后终末状态等特点，使其在失败病例的二次矫治中具有一定优势。本文通过展示无托槽隐形矫治在二次矫治病例中的应用实例，对矫治设计和监控细节进行讨论和总结。建议医师在接诊前利用无托槽隐形矫治难度评估工具对患者情况进行评估，接诊自身诊疗能力范围内的病例，以获得满意的矫治疗效。无托槽隐形矫治技术治疗减数病例的成功关键在于诊断正确，选对病例。在方案设计上，二次矫治应注意前牙转矩的恢复，利用推磨牙向后获得间隙，做好垂直向控制，改善后牙咬合关系。在无托槽隐形矫治中正确选择、谨慎纳入、合理设计，有望在二次矫治的疑难病例中获得牙排列整齐、尖窝交错、覆(牙合)覆盖正常、牙周健康、牙根平行的矫治效果，达到美观、功能、稳定、健康的矫治目标。.」

「Clear aligners have become a treatment alternative to metal brackets in recent years due to the advantages of aesthetics, comfort, and oral health improvement.」

「To evaluate the facial aesthetic effects of orthodontic treatment performed with clear aligners and to compare it to an untreated control group, on lower third facial ageing in adult patients through the use of the Wrinkle Severity Rating Scale (WSRS) at the beginning (T0) and at the end (T1) of the study period.」

「The greatest demand for orthodontic treatments comes from women, as they pay more attention to aesthetics, which makes the clear aligners the most common choice.」

「There was no association between sex, previous orthodontic treatment history, satisfaction with own dental appearance and potential interest in treatment and aligner visibility and willingness-to-pay.」

「With the advent of advanced appliances such as ceramic brackets, lingual braces, and clear aligners, alongside a growing emphasis on aesthetics and self-image, orthodontic care has become increasingly relevant for adults.」

「The precision of a 3D-printed dental model mainly relied on characteristics of photocurable resin, the resolution of light source and the exposure condition, which determined the eventual shape of the molded clear aligner and thus the orthodontic treatment efficacy.」

「Nevertheless, there are inherent risks and complications associated with short-term orthodontic treatments that are deliberately limited in their outcomes and these, together with the potential ramifications for the long-term dental health of patients, are discussed.」

「Recently, clear aligners have become a popular choice for orthodontic treatment, particularly among adults.」

「We envision that it would be an ideal alternative for patients who pursue esthetic orthodontic treatment but were not likely to take lingual appliances or clear aligners.」

「Proper selection of cases and reasonable design in clear aligner treatment are expected to obtain tooth alignment, good intercuspation, normal overbite and overjet, periodontal health, parallel roots, and to achieve the goal of aesthetic, functional, stable, and healthy orthodontic treatment. 术者诊断设计不当、矫治技术应用失误、正畸治疗后的复发以及患者依从性较差无法配合矫治等原因可导致患者对矫治结果不满意，寻求二次矫治。此类患者通常已减数，或伴牙周、关节、牙体或缺牙等问题，常需多学科联合治疗，二次矫治难度较大，可选方案受限。无托槽隐形矫治舒适美观，具备数字化精准化程度高、可个性化排牙模拟矫治后终末状态等特点，使其在失败病例的二次矫治中具有一定优势。本文通过展示无托槽隐形矫治在二次矫治病例中的应用实例，对矫治设计和监控细节进行讨论和总结。建议医师在接诊前利用无托槽隐形矫治难度评估工具对患者情况进行评估，接诊自身诊疗能力范围内的病例，以获得满意的矫治疗效。无托槽隐形矫治技术治疗减数病例的成功关键在于诊断正确，选对病例。在方案设计上，二次矫治应注意前牙转矩的恢复，利用推磨牙向后获得间隙，做好垂直向控制，改善后牙咬合关系。在无托槽隐形矫治中正确选择、谨慎纳入、合理设计，有望在二次矫治的疑难病例中获得牙排列整齐、尖窝交错、覆(牙合)覆盖正常、牙周健康、牙根平行的矫治效果，达到美观、功能、稳定、健康的矫治目标。.」

「Nevertheless, there are inherent risks and complications associated with short-term orthodontic treatments that are deliberately limited in their outcomes and these, together with the potential ramifications for the long-term dental health of patients, are discussed.」

「Clear aligners have become a treatment alternative to metal brackets in recent years due to the advantages of aesthetics, comfort, and oral health improvement.」

「To evaluate the facial aesthetic effects of orthodontic treatment performed with clear aligners and to compare it to an untreated control group, on lower third facial ageing in adult patients through the use of the Wrinkle Severity Rating Scale (WSRS) at the beginning (T0) and at the end (T1) of the study period.」

「The greatest demand for orthodontic treatments comes from women, as they pay more attention to aesthetics, which makes the clear aligners the most common choice.」

「There was no association between sex, previous orthodontic treatment history, satisfaction with own dental appearance and potential interest in treatment and aligner visibility and willingness-to-pay.」

「With the advent of advanced appliances such as ceramic brackets, lingual braces, and clear aligners, alongside a growing emphasis on aesthetics and self-image, orthodontic care has become increasingly relevant for adults.」

「The precision of a 3D-printed dental model mainly relied on characteristics of photocurable resin, the resolution of light source and the exposure condition, which determined the eventual shape of the molded clear aligner and thus the orthodontic treatment efficacy.」

「Recently, clear aligners have become a popular choice for orthodontic treatment, particularly among adults.」

「Clear aligner therapy has expanded substantially in mixed dentition, yet the boundaries of clinical predictability across indications, movement types, and growth stages remain incompletely defined.」

「To analyse through a systematic review the effectiveness of clear aligners by assessing: (a) predictability of clear aligners and (b) treatment outcome comparison of clear aligner therapy with fixed appliance therapy.」

「The content of the guidelines is based on monographs and literatures on the clear aligner orthodontic treatment in the past five years, and the clinical consensus of all the members of Expert Group for Writing Project of Clear Aligner Technology.」

「"Guidelines for clear aligner orthodontic treatment (2021)" proposes clinical treatment recommendations in terms of practitioner requirements, clinical risks, diagnosis, treatment plan, and common clinical strategies for the orthodontic clear aligners technology.」

「An internet search reveals at least 27 different clear aligner products currently on offer for orthodontic treatment.」

「Proper selection of cases and reasonable design in clear aligner treatment are expected to obtain tooth alignment, good intercuspation, normal overbite and overjet, periodontal health, parallel roots, and to achieve the goal of aesthetic, functional, stable, and healthy orthodontic treatment. 术者诊断设计不当、矫治技术应用失误、正畸治疗后的复发以及患者依从性较差无法配合矫治等原因可导致患者对矫治结果不满意，寻求二次矫治。此类患者通常已减数，或伴牙周、关节、牙体或缺牙等问题，常需多学科联合治疗，二次矫治难度较大，可选方案受限。无托槽隐形矫治舒适美观，具备数字化精准化程度高、可个性化排牙模拟矫治后终末状态等特点，使其在失败病例的二次矫治中具有一定优势。本文通过展示无托槽隐形矫治在二次矫治病例中的应用实例，对矫治设计和监控细节进行讨论和总结。建议医师在接诊前利用无托槽隐形矫治难度评估工具对患者情况进行评估，接诊自身诊疗能力范围内的病例，以获得满意的矫治疗效。无托槽隐形矫治技术治疗减数病例的成功关键在于诊断正确，选对病例。在方案设计上，二次矫治应注意前牙转矩的恢复，利用推磨牙向后获得间隙，做好垂直向控制，改善后牙咬合关系。在无托槽隐形矫治中正确选择、谨慎纳入、合理设计，有望在二次矫治的疑难病例中获得牙排列整齐、尖窝交错、覆(牙合)覆盖正常、牙周健康、牙根平行的矫治效果，达到美观、功能、稳定、健康的矫治目标。.」

「The study, based on the modified Delphi method, collected the opinion of experts, comparing it with the scientific literature to evaluate the potential and limitations of orthodontic aligners, obtaining 47 consensus statements related to biomechanics and extraclinical factors.」

「Clear aligner therapy (CAT) has rapidly evolved as a preferred orthodontic treatment option due to its aesthetic appeal, comfort, and removability.」

「Background and Objectives: Recent advances in dentistry include microbiological and metabolomic analyses, which have the potential to improve the understanding of oral microbiome-host imbalances during orthodontic treatment.」

「The concept of using clear aligners as a means of achieving tooth movement has increased in popularity among both patients and clinicians alike.」

「Clear aligner therapy has expanded substantially in mixed dentition, yet the boundaries of clinical predictability across indications, movement types, and growth stages remain incompletely defined.」

「To analyse through a systematic review the effectiveness of clear aligners by assessing: (a) predictability of clear aligners and (b) treatment outcome comparison of clear aligner therapy with fixed appliance therapy.」

「The content of the guidelines is based on monographs and literatures on the clear aligner orthodontic treatment in the past five years, and the clinical consensus of all the members of Expert Group for Writing Project of Clear Aligner Technology.」

「"Guidelines for clear aligner orthodontic treatment (2021)" proposes clinical treatment recommendations in terms of practitioner requirements, clinical risks, diagnosis, treatment plan, and common clinical strategies for the orthodontic clear aligners technology.」

「An internet search reveals at least 27 different clear aligner products currently on offer for orthodontic treatment.」

「Proper selection of cases and reasonable design in clear aligner treatment are expected to obtain tooth alignment, good intercuspation, normal overbite and overjet, periodontal health, parallel roots, and to achieve the goal of aesthetic, functional, stable, and healthy orthodontic treatment. 术者诊断设计不当、矫治技术应用失误、正畸治疗后的复发以及患者依从性较差无法配合矫治等原因可导致患者对矫治结果不满意，寻求二次矫治。此类患者通常已减数，或伴牙周、关节、牙体或缺牙等问题，常需多学科联合治疗，二次矫治难度较大，可选方案受限。无托槽隐形矫治舒适美观，具备数字化精准化程度高、可个性化排牙模拟矫治后终末状态等特点，使其在失败病例的二次矫治中具有一定优势。本文通过展示无托槽隐形矫治在二次矫治病例中的应用实例，对矫治设计和监控细节进行讨论和总结。建议医师在接诊前利用无托槽隐形矫治难度评估工具对患者情况进行评估，接诊自身诊疗能力范围内的病例，以获得满意的矫治疗效。无托槽隐形矫治技术治疗减数病例的成功关键在于诊断正确，选对病例。在方案设计上，二次矫治应注意前牙转矩的恢复，利用推磨牙向后获得间隙，做好垂直向控制，改善后牙咬合关系。在无托槽隐形矫治中正确选择、谨慎纳入、合理设计，有望在二次矫治的疑难病例中获得牙排列整齐、尖窝交错、覆(牙合)覆盖正常、牙周健康、牙根平行的矫治效果，达到美观、功能、稳定、健康的矫治目标。.」

「The study, based on the modified Delphi method, collected the opinion of experts, comparing it with the scientific literature to evaluate the potential and limitations of orthodontic aligners, obtaining 47 consensus statements related to biomechanics and extraclinical factors.」

「Clear aligner therapy (CAT) has rapidly evolved as a preferred orthodontic treatment option due to its aesthetic appeal, comfort, and removability.」

「Background and Objectives: Recent advances in dentistry include microbiological and metabolomic analyses, which have the potential to improve the understanding of oral microbiome-host imbalances during orthodontic treatment.」

「The concept of using clear aligners as a means of achieving tooth movement has increased in popularity among both patients and clinicians alike.」

「Clear aligner therapy has expanded substantially in mixed dentition, yet the boundaries of clinical predictability across indications, movement types, and growth stages remain incompletely defined.」

「To analyse through a systematic review the effectiveness of clear aligners by assessing: (a) predictability of clear aligners and (b) treatment outcome comparison of clear aligner therapy with fixed appliance therapy.」

「The content of the guidelines is based on monographs and literatures on the clear aligner orthodontic treatment in the past five years, and the clinical consensus of all the members of Expert Group for Writing Project of Clear Aligner Technology.」

「"Guidelines for clear aligner orthodontic treatment (2021)" proposes clinical treatment recommendations in terms of practitioner requirements, clinical risks, diagnosis, treatment plan, and common clinical strategies for the orthodontic clear aligners technology.」

「An internet search reveals at least 27 different clear aligner products currently on offer for orthodontic treatment.」

「Proper selection of cases and reasonable design in clear aligner treatment are expected to obtain tooth alignment, good intercuspation, normal overbite and overjet, periodontal health, parallel roots, and to achieve the goal of aesthetic, functional, stable, and healthy orthodontic treatment. 术者诊断设计不当、矫治技术应用失误、正畸治疗后的复发以及患者依从性较差无法配合矫治等原因可导致患者对矫治结果不满意，寻求二次矫治。此类患者通常已减数，或伴牙周、关节、牙体或缺牙等问题，常需多学科联合治疗，二次矫治难度较大，可选方案受限。无托槽隐形矫治舒适美观，具备数字化精准化程度高、可个性化排牙模拟矫治后终末状态等特点，使其在失败病例的二次矫治中具有一定优势。本文通过展示无托槽隐形矫治在二次矫治病例中的应用实例，对矫治设计和监控细节进行讨论和总结。建议医师在接诊前利用无托槽隐形矫治难度评估工具对患者情况进行评估，接诊自身诊疗能力范围内的病例，以获得满意的矫治疗效。无托槽隐形矫治技术治疗减数病例的成功关键在于诊断正确，选对病例。在方案设计上，二次矫治应注意前牙转矩的恢复，利用推磨牙向后获得间隙，做好垂直向控制，改善后牙咬合关系。在无托槽隐形矫治中正确选择、谨慎纳入、合理设计，有望在二次矫治的疑难病例中获得牙排列整齐、尖窝交错、覆(牙合)覆盖正常、牙周健康、牙根平行的矫治效果，达到美观、功能、稳定、健康的矫治目标。.」

「The study, based on the modified Delphi method, collected the opinion of experts, comparing it with the scientific literature to evaluate the potential and limitations of orthodontic aligners, obtaining 47 consensus statements related to biomechanics and extraclinical factors.」

「Clear aligner therapy (CAT) has rapidly evolved as a preferred orthodontic treatment option due to its aesthetic appeal, comfort, and removability.」

「Background and Objectives: Recent advances in dentistry include microbiological and metabolomic analyses, which have the potential to improve the understanding of oral microbiome-host imbalances during orthodontic treatment.」

「The concept of using clear aligners as a means of achieving tooth movement has increased in popularity among both patients and clinicians alike.」

「Clear aligner therapy has expanded substantially in mixed dentition, yet the boundaries of clinical predictability across indications, movement types, and growth stages remain incompletely defined.」

「To analyse through a systematic review the effectiveness of clear aligners by assessing: (a) predictability of clear aligners and (b) treatment outcome comparison of clear aligner therapy with fixed appliance therapy.」

「The content of the guidelines is based on monographs and literatures on the clear aligner orthodontic treatment in the past five years, and the clinical consensus of all the members of Expert Group for Writing Project of Clear Aligner Technology.」

「"Guidelines for clear aligner orthodontic treatment (2021)" proposes clinical treatment recommendations in terms of practitioner requirements, clinical risks, diagnosis, treatment plan, and common clinical strategies for the orthodontic clear aligners technology.」

「An internet search reveals at least 27 different clear aligner products currently on offer for orthodontic treatment.」

「Proper selection of cases and reasonable design in clear aligner treatment are expected to obtain tooth alignment, good intercuspation, normal overbite and overjet, periodontal health, parallel roots, and to achieve the goal of aesthetic, functional, stable, and healthy orthodontic treatment. 术者诊断设计不当、矫治技术应用失误、正畸治疗后的复发以及患者依从性较差无法配合矫治等原因可导致患者对矫治结果不满意，寻求二次矫治。此类患者通常已减数，或伴牙周、关节、牙体或缺牙等问题，常需多学科联合治疗，二次矫治难度较大，可选方案受限。无托槽隐形矫治舒适美观，具备数字化精准化程度高、可个性化排牙模拟矫治后终末状态等特点，使其在失败病例的二次矫治中具有一定优势。本文通过展示无托槽隐形矫治在二次矫治病例中的应用实例，对矫治设计和监控细节进行讨论和总结。建议医师在接诊前利用无托槽隐形矫治难度评估工具对患者情况进行评估，接诊自身诊疗能力范围内的病例，以获得满意的矫治疗效。无托槽隐形矫治技术治疗减数病例的成功关键在于诊断正确，选对病例。在方案设计上，二次矫治应注意前牙转矩的恢复，利用推磨牙向后获得间隙，做好垂直向控制，改善后牙咬合关系。在无托槽隐形矫治中正确选择、谨慎纳入、合理设计，有望在二次矫治的疑难病例中获得牙排列整齐、尖窝交错、覆(牙合)覆盖正常、牙周健康、牙根平行的矫治效果，达到美观、功能、稳定、健康的矫治目标。.」

「The study, based on the modified Delphi method, collected the opinion of experts, comparing it with the scientific literature to evaluate the potential and limitations of orthodontic aligners, obtaining 47 consensus statements related to biomechanics and extraclinical factors.」

「Clear aligner therapy (CAT) has rapidly evolved as a preferred orthodontic treatment option due to its aesthetic appeal, comfort, and removability.」

「Background and Objectives: Recent advances in dentistry include microbiological and metabolomic analyses, which have the potential to improve the understanding of oral microbiome-host imbalances during orthodontic treatment.」

「The concept of using clear aligners as a means of achieving tooth movement has increased in popularity among both patients and clinicians alike.」

「Clear aligners and fixed braces are two common orthodontic treatments.」

「Background The continuous increase in demand for reduced treatment times has led researchers to think in terms of "accelerated orthodontics." Generally, the duration for fixed orthodontic treatment is around two to three years.」

「BackgroundOrthodontic clear aligners are a technologically advanced treatment modality that improves aesthetics and comfort while impacting patients' oral health-related quality of life (OHRQoL).ObjectiveThis study assessed and compared the OHRQoL of adult orthodontic patients receiving clear aligners and fixed appliances (metal and ceramic brackets) during orthodontic treatments.MethodologyOne hundred and five orthodontic patients were recruited and classified according to the treatment received.」

「The OHRQoL of patients was assessed by the short-form Oral Health Impact Profile (OHIP-14) at the following assessment times: before the start of treatment (T0), 1 week (T1), 1 month (T2), 3 months (T3), and 6 months (T4) after the start of orthodontic treatment and post-treatment (T5).」

「OHRQoL was assessed using the OHIP-14 tool at various times during comprehensive orthodontic therapy: baseline (T0), one week (T1), two weeks (T2), one month (T3), 6 months (T4), and 12 months (T5) after starting the active orthodontic treatment.」

「Design Non-randomised cohort study.Cohort selection The inclusion criteria comprised patients who finished their comprehensive orthodontic treatment based on a camouflage non-extraction modality using self-ligating orthodontic appliances therapy (SPEED brackets, Canada or Empower brackets, American Ortho, Sheboygan, WI, USA) or clear aligner therapy (Invisalign, Align Technology, San Jose, CA, USA).」

「The mean treatment duration in the 7-day aligner change group was nearly half that of the 14-day aligner change group (5 months vs 9 months).」

「Fixed orthodontic treatment (FOT) typically lasts 14-33 months, with regular appointments at short intervals to monitor changes, adjust appliances, and remotivate patients to maintain excellent oral hygiene standards to prevent dental disease.」

「The aim of this study was to evaluate the MID in orthodontic treatment duration to inform the decision regarding seeking procedures to accelerate orthodontic tooth movement and reduce treatment duration.」

「In the literature, no consensus has been reached about orthodontic treatment time.」

「Orthodontic treatment is a widely embraced intervention aimed at enhancing dental aesthetics and correcting malocclusions among adolescents.」

「Structured oral hygiene guidance during orthodontic treatment is crucial to reduce caries risk and improve long-term oral health outcomes.」

「However, over a lengthy period of orthodontic treatment, enamel demineralization or even dental caries could be susceptible for occurrence.」

「A consistent positive correlation between clear aligner and dental caries was observed across all three years (p < 0.05).」

「Orthodontic treatment has been suggested to increase the risk of dental caries.」

「Fixed appliances, functional devices and, more recently, clear aligners have been associated with several oral health conditions, including enamel demineralization, dental caries, gingivitis, periodontitis and root and bone resorption.」

「Introducing orthodontic treatments, such as aligners and fixed appliances, might impact this microbial ecosystem.」

「To assess the influence of orthodontic treatment on long-term caries experience in 30-year-old South Australians.」

「However, the early stage caries, a most common complication in patients receiving orthodontic treatment using fixed appliances, has become a serious challenge to the prevention of dental caries and the esthetic outcome of orthodontic treatment.」

「Dental Caries is one of the common complications in patients undergoing orthodontic treatment.」

「Clear aligner therapy has expanded substantially in mixed dentition, yet the boundaries of clinical predictability across indications, movement types, and growth stages remain incompletely defined.」

「To analyse through a systematic review the effectiveness of clear aligners by assessing: (a) predictability of clear aligners and (b) treatment outcome comparison of clear aligner therapy with fixed appliance therapy.」

「The content of the guidelines is based on monographs and literatures on the clear aligner orthodontic treatment in the past five years, and the clinical consensus of all the members of Expert Group for Writing Project of Clear Aligner Technology.」

「"Guidelines for clear aligner orthodontic treatment (2021)" proposes clinical treatment recommendations in terms of practitioner requirements, clinical risks, diagnosis, treatment plan, and common clinical strategies for the orthodontic clear aligners technology.」

「An internet search reveals at least 27 different clear aligner products currently on offer for orthodontic treatment.」

「Proper selection of cases and reasonable design in clear aligner treatment are expected to obtain tooth alignment, good intercuspation, normal overbite and overjet, periodontal health, parallel roots, and to achieve the goal of aesthetic, functional, stable, and healthy orthodontic treatment. 术者诊断设计不当、矫治技术应用失误、正畸治疗后的复发以及患者依从性较差无法配合矫治等原因可导致患者对矫治结果不满意，寻求二次矫治。此类患者通常已减数，或伴牙周、关节、牙体或缺牙等问题，常需多学科联合治疗，二次矫治难度较大，可选方案受限。无托槽隐形矫治舒适美观，具备数字化精准化程度高、可个性化排牙模拟矫治后终末状态等特点，使其在失败病例的二次矫治中具有一定优势。本文通过展示无托槽隐形矫治在二次矫治病例中的应用实例，对矫治设计和监控细节进行讨论和总结。建议医师在接诊前利用无托槽隐形矫治难度评估工具对患者情况进行评估，接诊自身诊疗能力范围内的病例，以获得满意的矫治疗效。无托槽隐形矫治技术治疗减数病例的成功关键在于诊断正确，选对病例。在方案设计上，二次矫治应注意前牙转矩的恢复，利用推磨牙向后获得间隙，做好垂直向控制，改善后牙咬合关系。在无托槽隐形矫治中正确选择、谨慎纳入、合理设计，有望在二次矫治的疑难病例中获得牙排列整齐、尖窝交错、覆(牙合)覆盖正常、牙周健康、牙根平行的矫治效果，达到美观、功能、稳定、健康的矫治目标。.」

「The study, based on the modified Delphi method, collected the opinion of experts, comparing it with the scientific literature to evaluate the potential and limitations of orthodontic aligners, obtaining 47 consensus statements related to biomechanics and extraclinical factors.」

「Clear aligner therapy (CAT) has rapidly evolved as a preferred orthodontic treatment option due to its aesthetic appeal, comfort, and removability.」

「Background and Objectives: Recent advances in dentistry include microbiological and metabolomic analyses, which have the potential to improve the understanding of oral microbiome-host imbalances during orthodontic treatment.」

「The concept of using clear aligners as a means of achieving tooth movement has increased in popularity among both patients and clinicians alike.」

「Proper selection of cases and reasonable design in clear aligner treatment are expected to obtain tooth alignment, good intercuspation, normal overbite and overjet, periodontal health, parallel roots, and to achieve the goal of aesthetic, functional, stable, and healthy orthodontic treatment. 术者诊断设计不当、矫治技术应用失误、正畸治疗后的复发以及患者依从性较差无法配合矫治等原因可导致患者对矫治结果不满意，寻求二次矫治。此类患者通常已减数，或伴牙周、关节、牙体或缺牙等问题，常需多学科联合治疗，二次矫治难度较大，可选方案受限。无托槽隐形矫治舒适美观，具备数字化精准化程度高、可个性化排牙模拟矫治后终末状态等特点，使其在失败病例的二次矫治中具有一定优势。本文通过展示无托槽隐形矫治在二次矫治病例中的应用实例，对矫治设计和监控细节进行讨论和总结。建议医师在接诊前利用无托槽隐形矫治难度评估工具对患者情况进行评估，接诊自身诊疗能力范围内的病例，以获得满意的矫治疗效。无托槽隐形矫治技术治疗减数病例的成功关键在于诊断正确，选对病例。在方案设计上，二次矫治应注意前牙转矩的恢复，利用推磨牙向后获得间隙，做好垂直向控制，改善后牙咬合关系。在无托槽隐形矫治中正确选择、谨慎纳入、合理设计，有望在二次矫治的疑难病例中获得牙排列整齐、尖窝交错、覆(牙合)覆盖正常、牙周健康、牙根平行的矫治效果，达到美观、功能、稳定、健康的矫治目标。.」

「"Guidelines for clear aligner orthodontic treatment (2021)" proposes clinical treatment recommendations in terms of practitioner requirements, clinical risks, diagnosis, treatment plan, and common clinical strategies for the orthodontic clear aligners technology.」

「An internet search reveals at least 27 different clear aligner products currently on offer for orthodontic treatment.」

「The content of the guidelines is based on monographs and literatures on the clear aligner orthodontic treatment in the past five years, and the clinical consensus of all the members of Expert Group for Writing Project of Clear Aligner Technology.」

「The concept of using clear aligners as a means of achieving tooth movement has increased in popularity among both patients and clinicians alike.」

「The objective of this study is to evaluate and compare the initial changes of pulpal blood flow (PBF) using clear aligner and fixed orthodontic treatment.」

「Combining clear aligner therapy and fixed lingual appliance is an esthetic means of treating malocclusions in a shorter treatment time with low costs and high efficiency.」

「Digital orthodontic treatment has revolutionized clinical practice, yet predicting individual patient outcomes remains challenging.」

「In this paper,the problems related with adult orthodontic treatment were reviewed.」

「This study investigated the effects of different mini-screw anchorage techniques on the three-dimensional (3D) movement of anterior and posterior teeth during maxillary anterior retraction with clear aligners in extraction cases, aiming to provide guidance for clinical orthodontic practice.」

「Clear aligner therapy has expanded substantially in mixed dentition, yet the boundaries of clinical predictability across indications, movement types, and growth stages remain incompletely defined.」

「To analyse through a systematic review the effectiveness of clear aligners by assessing: (a) predictability of clear aligners and (b) treatment outcome comparison of clear aligner therapy with fixed appliance therapy.」

「The content of the guidelines is based on monographs and literatures on the clear aligner orthodontic treatment in the past five years, and the clinical consensus of all the members of Expert Group for Writing Project of Clear Aligner Technology.」

「"Guidelines for clear aligner orthodontic treatment (2021)" proposes clinical treatment recommendations in terms of practitioner requirements, clinical risks, diagnosis, treatment plan, and common clinical strategies for the orthodontic clear aligners technology.」

「An internet search reveals at least 27 different clear aligner products currently on offer for orthodontic treatment.」

「Proper selection of cases and reasonable design in clear aligner treatment are expected to obtain tooth alignment, good intercuspation, normal overbite and overjet, periodontal health, parallel roots, and to achieve the goal of aesthetic, functional, stable, and healthy orthodontic treatment. 术者诊断设计不当、矫治技术应用失误、正畸治疗后的复发以及患者依从性较差无法配合矫治等原因可导致患者对矫治结果不满意，寻求二次矫治。此类患者通常已减数，或伴牙周、关节、牙体或缺牙等问题，常需多学科联合治疗，二次矫治难度较大，可选方案受限。无托槽隐形矫治舒适美观，具备数字化精准化程度高、可个性化排牙模拟矫治后终末状态等特点，使其在失败病例的二次矫治中具有一定优势。本文通过展示无托槽隐形矫治在二次矫治病例中的应用实例，对矫治设计和监控细节进行讨论和总结。建议医师在接诊前利用无托槽隐形矫治难度评估工具对患者情况进行评估，接诊自身诊疗能力范围内的病例，以获得满意的矫治疗效。无托槽隐形矫治技术治疗减数病例的成功关键在于诊断正确，选对病例。在方案设计上，二次矫治应注意前牙转矩的恢复，利用推磨牙向后获得间隙，做好垂直向控制，改善后牙咬合关系。在无托槽隐形矫治中正确选择、谨慎纳入、合理设计，有望在二次矫治的疑难病例中获得牙排列整齐、尖窝交错、覆(牙合)覆盖正常、牙周健康、牙根平行的矫治效果，达到美观、功能、稳定、健康的矫治目标。.」

「The study, based on the modified Delphi method, collected the opinion of experts, comparing it with the scientific literature to evaluate the potential and limitations of orthodontic aligners, obtaining 47 consensus statements related to biomechanics and extraclinical factors.」

「Clear aligner therapy (CAT) has rapidly evolved as a preferred orthodontic treatment option due to its aesthetic appeal, comfort, and removability.」

「Correcting malocclusions with controlled dental displacement is one of the objectives of orthodontic treatment.」

「Background and Objectives: Recent advances in dentistry include microbiological and metabolomic analyses, which have the potential to improve the understanding of oral microbiome-host imbalances during orthodontic treatment.」